Complications due to Obesity

• Type 2 Diabetes
• Hyperlipidemia
• Hypertension
• Cardiovascular Diseases
• Cerebrovascular Diseases
• Osteoarthritis • Fatty Liver (Steatosis)
• Higher Cancer Risk
• Gastroesophageal Reflux Diseases (GERD)
• Sleep Apnoea
• Venous Thrombosis
• Polycystic Ovary Syndrome

With the help of cardiac magnetic resonance imaging, the recent research has confirmed that there are structural changes in the heart. This proves that there is a direct link between the size of the left ventricle, fat tissue and BMI. Other studies have shown that there is a connection between obesity and dementia (including Alzheimer’s disease), with an increase in death rates. Although most people are concerned with obesity due to aesthetic reasons, it is important to keep in mind that it is primarily a health problem. An increase in body weight gives rise to a number of clinical complications which lower the overall quality of life, the ability to work and the lifespan of the diseased. Obesity is an important predisposing factor for coronary heart disease, cerebrovascular insult, arterial hypertension, dyslipidemia, diabetes mellitus type 2 and sleep apnoea syndrome. Malignant diseases which are being related to obesity are breast cancer, uterus cancer, colon cancer, prostate cancer and tumours of the hepatobiliary system. Complications due to obesity include diseases of the gastrointestinal tract, degenerative wrist diseases, polycystic ovary syndrome, infertility and an entire series of psychological problems. At the level of pathophysiological obesity is closely connected to a series of mechanisms which affect the development of certain disorders, which progress and interact and lead to premature death. So far, the research was most commonly directed towards the role of chronic generalized inflammation, endothelial dysfunction, insulin resistance and hypercoagulability, as the main pathophysiological mechanisms responsible for the development of atherosclerosis in the obese, that is, the high cardiovascular risk connected to obesity.